Religious Popular Music: Between the Instrumental, Transcendent and Transgressive

The use of post-rock ‘n’ roll popular music genres by religious groups is accompanied by a notable ambiguity: Is religious popular music designed to be an instrumental tool for outreach/evangelism, or does it have an intrinsic value in summoning and exploring the transcendent? The article focuses on the previously rarely explored idea that the instrumental use of popular music in Christian andJewish settings is often much more important than its transcendent qualities. The importance of the instrumental in Christian and Jewish popular music reveals itself in subtle and not-so-subtle signifiers and practices that point to an anxious desire to discipline music’s possible transgressive force

A tutorial on the characterisation and modelling of low layer functional splits for flexible radio access networks in 5G and beyond

The centralization of baseband (BB) functions in a radio access network (RAN) towards data processing centres is receiving increasing interest as it enables the exploitation of resource pooling and statistical multiplexing gains among multiple cells, facilitates the introduction of collaborative techniques for different functions (e.g., interference coordination), and more efficiently handles the complex requirements of advanced features of the fifth generation (5G) new radio (NR) physical layer, such as the use of massive multiple input multiple output (MIMO). However, deciding the functional split (i.e., which BB functions are kept close to the radio units and which BB functions are centralized) embraces a trade-off between the centralization benefits and the fronthaul costs for carrying data between distributed antennas and data processing centres. Substantial research efforts have been made in standardization fora, research projects and studies to resolve this trade-off, which becomes more complicated when the choice of functional splits is dynamically achieved depending on the current conditions in the RAN. This paper presents a comprehensive tutorial on the characterisation, modelling and assessment of functional splits in a flexible RAN to establish a solid basis for the future development of algorithmic solutions of dynamic functional split optimisation in 5G and beyond systems. First, the paper explores the functional split approaches considered by different industrial fora, analysing their equivalences and differences in terminology. Second, the paper presents a harmonized analysis of the different BB functions at the physical layer and associated algorithmic solutions presented in the literature, assessing both the computational complexity and the associated performance. Based on this analysis, the paper presents a model for assessing the computational requirements and fronthaul bandwidth requirements of different functional splits. Last, the model is used to derive illustrative results that identify the major trade-offs that arise when selecting a functional split and the key elements that impact the requirements.This work has been partially funded by Huawei Technologies. Work by X. Gelabert and B. Klaiqi is partially funded by the European Union's Horizon Europe research and innovation programme (HORIZON-MSCA-2021-DN-0) under the Marie Skłodowska-Curie grant agreement No 101073265. Work by J. Perez-Romero and O. Sallent is also partially funded by the Smart Networks and Services Joint Undertaking (SNS JU) under the European Union’s Horizon Europe research and innovation programme under Grant Agreements No. 101096034 (VERGE project) and No. 101097083 (BeGREEN project) and by the Spanish Ministry of Science and Innovation MCIN/AEI/10.13039/501100011033 under ARTIST project (ref. PID2020-115104RB-I00). This last project has also funded the work by D. Campoy.Peer ReviewedPostprint (author's final draft

Desert Dust Air Mass Mapping in the Western Sahara, using Particle Properties Derived from Space-based Multi-angle Imaging

Coincident observations made over the Moroccan desert during the SAhara Mineral dUst experiMent (SAMUM) 2006 field campaign are used both to validate aerosol amount and type retrieved from Multi-angle Imaging SpectroRadiometer (MISR) observations, and to place the sub-orbital aerosol measurements into the satellite's larger regional context. On three moderately dusty days for which coincident observations were made, MISR mid-visible aerosol optical thickness (AOT) agrees with field measurements point-by-point to within 0.05 to 0.1. This is about as well as can be expected given spatial sampling differences; the space-based observations capture AOT trends and variability over an extended region. The field data also validate MISR's ability to distinguish and to map aerosol air masses, from the combination of retrieved constraints on particle size, shape, and single-scattering albedo. For the three study days, the satellite observations (a) highlight regional gradients in the mix of dust and background spherical particles, (b) identify a dust plume most likely part of a density flow, and (c) show an air mass containing a higher proportion of small, spherical particles than the surroundings, that appears to be aerosol pollution transported from several thousand kilometers away

Reaching for the 'first 95': a cross-country analysis of HIV self-testing in nine countries in sub-Saharan Africa

OBJECTIVES: HIV self-testing (HIVST) offers a promising approach to increase HIV diagnosis and advance progress towards the UNAIDS 95-95-95 targets. We aimed to understand patterns of HIVST awareness and utilization in nine sub-Saharan African (SSA) countries, with the goal of identifying populations to target in disseminating this technology. DESIGN: A cross-sectional study. METHODS: We pooled individual-level population-based data from nine Demographic and Health Surveys (DHS) in SSA conducted 2015-2019 (Burundi, Cameroon, Guinea, Malawi, Senegal, Sierra Leone, South Africa, Zambia, Zimbabwe). Primary outcomes were HIVST awareness and utilization. We used logistic regression with survey fixed effects to explore the relationship between sociodemographic characteristics and these outcomes. Models were adjusted for sex, age, rural/urban residence, education, wealth, and marital status. We accounted for complex survey design. RESULTS: The study sample included 177 572 people (66.0% women, mean age 29 ± 10 years), of whom 86.6% [95% confidence interval (95% CI) 86.4-86.7] were unaware of HIVST, 11.7% (95% CI 11.6-11.9) were aware of but never used HIVST, and 1.7% (95% CI 1.6-1.8) had used HIVST. In adjusted models, women were less likely to be aware of HIVST [odds ratio (OR) 0.75, 95% CI 0.71-0.79], but more likely to have used HIVST (OR 1.17, 95% CI 1.03-1.32) compared with men. Rural residents, those who were least educated, and poorest were less likely to have heard of or used HIVST. CONCLUSION: HIVST awareness and uptake were low. Rural, less educated, and lower income populations were least likely to have heard of or used HIVST. Efforts to scale-up HIVST in these settings should aim to reach these less advantaged groups

Sensitivity of Lipid Metabolism and Insulin Signaling to Genetic Alterations in Hepatic Peroxisome Proliferator–Activated Receptor-γ\gamma Coactivator-1α\alpha Expression

Objective: The peroxisome proliferator–activated receptor-$\gamma$ coactivator (PGC)-1 family of transcriptional coactivators controls hepatic function by modulating the expression of key metabolic enzymes. Hepatic gain of function and complete genetic ablation of PGC-1$\alpha$ show that this coactivator is important for activating the programs of gluconeogenesis, fatty acid oxidation, oxidative phosphorylation, and lipid secretion during times of nutrient deprivation. However, how moderate changes in PGC-1$\alpha$ activity affect metabolism and energy homeostasis has yet to be determined. Research Design and Methods: To identify key metabolic pathways that may be physiologically relevant in the context of reduced hepatic PGC-1$\alpha$ levels, we used the Cre/Lox system to create mice heterozygous for PGC-1$\alpha$ specifically within the liver (LH mice). Results: These mice showed fasting hepatic steatosis and diminished ketogenesis associated with decreased expression of genes involved in mitochondrial $\beta$-oxidation. LH mice also exhibited high circulating levels of triglyceride that correlated with increased expression of genes involved in triglyceride-rich lipoprotein assembly. Concomitant with defects in lipid metabolism, hepatic insulin resistance was observed both in LH mice fed a high-fat diet as well as in primary hepatocytes. Results: These data highlight both the dose-dependent and long-term effects of reducing hepatic PGC-1$\alpha$ levels, underlining the importance of tightly regulated PGC-1$\alpha$ expression in the maintenance of lipid homeostasis and glucose metabolism

Desert dust aerosol air mass mapping in the western Sahara, using particle properties derived from space-based multi-angle imaging

Coincident observations made over the Moroccan desert during the Sahara mineral dust experiment (SAMUM) 2006 field campaign are used both to validate aerosol amount and type retrieved from multi-angle imaging spectroradiometer (MISR) observations, and to place the suborbital aerosol measurements into the satellite’s larger regional context. On three moderately dusty days during which coincident observations were made, MISR mid-visible aerosol optical thickness (AOT) agrees with field measurements point-by-point to within 0.05–0.1. This is about as well as can be expected given spatial sampling differences; the space-based observations capture AOT trends and variability over an extended region. The field data also validate MISR’s ability to distinguish and to map aerosol air masses, from the combination of retrieved constraints on particle size, shape and single-scattering albedo. For the three study days, the satellite observations (1) highlight regional gradients in the mix of dust and background spherical particles, (2) identify a dust plume most likely part of a density flow and (3) show an aerosol air mass containing a higher proportion of small, spherical particles than the surroundings, that appears to be aerosol pollution transported from several thousand kilometres away

Concentration Dependence of Superconductivity and Order-Disorder Transition in the Hexagonal Rubidium Tungsten Bronze RbxWO3. Interfacial and bulk properties

We revisited the problem of the stability of the superconducting state in RbxWO3 and identified the main causes of the contradictory data previously published. We have shown that the ordering of the Rb vacancies in the nonstoichiometric compounds have a major detrimental effect on the superconducting temperature Tc.The order-disorder transition is first order only near x = 0.25, where it cannot be quenched effectively and Tc is reduced below 1K. We found that the high Tc's which were sometimes deduced from resistivity measurements, and attributed to compounds with .25 < x < .30, are to be ascribed to interfacial superconductivity which generates spectacular non-linear effects. We also clarified the effect of acid etching and set more precisely the low-rubidium-content boundary of the hexagonal phase.This work makes clear that Tc would increase continuously (from 2 K to 5.5 K) as we approach this boundary (x = 0.20), if no ordering would take place - as its is approximately the case in CsxWO3. This behaviour is reminiscent of the tetragonal tungsten bronze NaxWO3 and asks the same question : what mechanism is responsible for this large increase of Tc despite the considerable associated reduction of the electron density of state ? By reviewing the other available data on these bronzes we conclude that the theoretical models which are able to answer this question are probably those where the instability of the lattice plays a major role and, particularly, the model which call upon local structural excitations (LSE), associated with the missing alkali atoms.Comment: To be published in Physical Review

Physical activity mass media campaigns and their evaluation: a systematic review of the literature 2003–2010

Internationally, mass media campaigns to promote regular moderate-intensity physical activity have increased recently. Evidence of mass media campaign effectiveness exists in other health areas, however the evidence for physical activity is limited. The purpose was to systematically review the literature on physical activity mass media campaigns, 2003–2010. A focus was on reviewing evaluation designs, theory used, formative evaluation, campaign effects and outcomes. Literature was searched resulting in 18 individual adult mass media campaigns, mostly in high-income regions and two in middle-income regions. Designs included: quasi experimental (n = 5); non experimental (n = 12); a mixed methods design (n = 1). One half used formative research. Awareness levels ranged from 17 to 95%. Seven campaigns reported significant increases in physical activity levels. The review found that beyond awareness raising, changes in other outcomes were measured, assessed but reported in varying ways. It highlighted improvements in evaluation, although limited evidence of campaign effects remain. It provides an update on the evaluation methodologies used in the adult literature. We recommend optimal evaluation design should include: (1) formative research to inform theories/frameworks, campaign content and evaluation design; (2) cohort study design with multiple data collection points; (3) sufficient duration; (4) use of validated measures; (5) sufficient evaluation resources

Obesity, fat distribution, and risk of frailty in two population-based cohorts of older adults in Spain

OBJECTIVE: To evaluate for the first time the longitudinal relationship between abdominal obesity and the onset of frailty. METHODS: Study based on results from two population-based cohorts, the Seniors-ENRICA, with 1801 individuals aged ≥60, and the Toledo Study for Healthy Ageing (TSHA), with 1289 participants ≥65 years. Incident frailty was assessed with the Fried criteria. RESULTS: During 3.5 years of follow-up, 125 individuals with incident frailty in Seniors-ENRICA and 162 in TSHA were identified. After adjustment for the main confounders, the pooled odds ratio (pooled OR) for general obesity and risk of frailty was 1.73 (95% confidence interval [CI]: 1.18-2.28). Abdominal obesity was also associated with frailty (pooled OR: 1.67; 95% CI: 1.09-2.25). Compared with individuals with BMI <25 kg/m(2) and no abdominal obesity, the risk of frailty was highest among individuals with concurrent general and abdominal obesity (pooled OR: 2.55; 95% CI: 1.23-3.86). General obesity was associated with increased risk of exhaustion (pooled OR: 1.66; 95% CI: 1.11-2.21), low physical activity (pooled OR: 1.57; 95% CI: 1.08-2.05), and weakness (pooled OR: 1.63; 95% CI: 1.12-2.05). For abdominal obesity, results were in the same direction, although they showed statistical significance only for weakness (OR: 1.46; 95% CI: 1.11-1.80)This work has been supported by grants from the Instituto de Salud Carlos III (PI12/1166, PI11/01379, PI13/00288 and RD12/0043/0001 RETICEF) and the European Commission (FRAILOMIC Initiative FP7-HEALTH-2012-Proposal No: 305483-2